Bio Protocol

September’s research updates from across the Bio ecosystem are here.

From @anagenxyz (HairDAO)'s early human pilot of slow-release minoxidil to @peptai_'s protein design competition entry, catch up on the work teams are working on↓

Have a peptide or protein design project in mind?

We’re looking to partner with researchers who bring deep biological expertise to take projects from computational design to wet lab validation.

Tell us about your project at the link below ↓

Being able to test a biological hypothesis digitally before committing to a lab experiment would change how we do science.

If these models become reliable enough, researchers could explore more possibilities and use the predictions to decide which experiments to run next.

Making those datasets open matters. A team working on a different disease can build on them, ask questions the original researchers never considered, and share what they find.

We're entering a new era of biology.

September in the Biosphere 🌐

- Open Science Index: We launched a searchable directory with 6,720 scientific resources.

- Launchpad: We added credit-card wallet funding through Privy.

- New Bio website: We revamped our website, bringing BIOS, OpenLabs, Buildspace, Launchpad and Biofy together in one place.

- PeptAI: Selected for Track 2 of the Adaptyv Bio × Anthropic Protein Design Competition.

- NeuroLab Ignition Sale: The sale closed 2.2× oversubscribed, with more than 442K USDC committed by over 650 participants. NDT reward claims for veBIO stakers are now live on app.bio.xyz. We also refunded all BioXP spent on the Ignition Sale.

Read the full monthly report ↓

BioXP Refund Update

All BioXP spent in the NeuroLab Ignition Sale has been refunded to every participant including those who purchased instant BioXP.

Refunds are automatic. No action is needed. Check your transaction history on the BioXP page: app.bio.xyz/bioxp

A full list of BioXP pledges and their resulting allocations will be available on the sale page shortly.

We're working closely with the NeuroLab team to support the project's long-term research and commercial development. Stay tuned for further updates.

Update on NeuroLabs Ignition Sale

We want to clarify what happened during the launch and what we’re changing going forward.

1. Based on past launches, we intentionally didn’t communicate a specific finalization time to allow a buffer for the launch to finalize and for us to verify that everything was correct before distributing allocations. However, an outdated message from a previous deployment was still displayed on the finalization page, stating it would happen within 30 minutes. A disruption to our subgraph infrastructure delayed finalization leaving about an hour between the sale ending and TGE. We’re sorry for the wait.

2. We saw concerns about a wallet receiving tokens without participating in the Ignition Sale and selling shortly after. This wallet belonged to a NeuroLabs advisor and had been funded just before the launch. The advisor sold tokens representing 2.15% of the total supply.

NeuroLabs AI's tokenomics allocated 14.83% of the total supply to advisors, fully liquid at launch as communicated on the Bio launchpad sale page. We always recommend vesting for team, investor and advisor allocations but accepted the team's request to make the advisor allocation fully liquid for this launch. Going forward, we’ll enforce vesting for all team, investor and advisor allocations to better protect supporters.

3. From our side, we will refund all BioXP spent on the sale to all participants including those who purchased instant BioXP.

We believe DeSci should give projects the funding and community support to deliver on their roadmaps beyond the TGE.

We're building towards this through early community building and funding on OpenLabs, with permissionless launches and milestone-based funding in development for the Bio launchpad. The goal is to let projects focus on their scientific work, with supporters committed to that longer-term progress.

Thank you for your patience and continued trust as we build an ecosystem of tools and communities to move science forward.

The $NDT token is officially live on @base.

Claim NDT on the Bio App: app.bio.xyz/agents/neurola…

CA: 0xd89e13e5faee17a8b4dd0739e0a9cab12b3828e3

→ NDT rewards are now live and claimable on the Bio app.

→ veBIO holders receive 20% of the total supply, 6-month linear vesting with 20% redeemable at TGE. Claiming early forfeits any unvested tokens.

Check out the NDT roadmap below

Congratulations @NootropicsDAO_ on a successful close!

AI can generate more hypotheses. Lab time and research budgets still determine which ones get tested.

A new @GoogleDeepMind preprint explores how scientists and AI agents could coordinate those resources. It cites @cl2pp’s work on IP-NFTs and how BioDAOs fund early-stage research.

With BIOS and OpenLabs, we’re working to turn scientific ideas into fundable, tradable assets faster.

Thanks @weballergy and co-authors for exploring how agentic science could work in practice.

Our Head of BD, Michelangelo (@oxMichelangelo) will be at @ARDD_Meeting in Boston this week until Saturday.

If you're building in consumer biotech, rare diseases or longevity and $25–150K could fund your next research step, DM him to meet.

We’d also love to chat if you’re an investor with promising projects that are still too early for your fund.

Congrats to the PeptAI team on being selected for Track 2 of the @adaptyvbio x @AnthropicAI Protein Design Competition!

Great to see the team joining researchers from around the world to advance AI-driven protein design and put new designs to the test.

Follow @peptai_ to track their progress ↓

An early experiment should clarify a decision: continue, change course, or stop.

A negative result can save months of work.

The hard part is funding that test before there’s a success story. Bio helps research teams raise community backing for the next milestone.

A virtual biotech company with tens of thousands of AI scientists.

A glimpse of how research could be organized: researchers set the direction, specialist agents work through the evidence and suggest what to test in the lab.

We’d like to see more researchers get a chance to put their ideas to the test.

Finding the right open source scientific software shouldn't be the hard part of your research.

Open Science Index groups tools by scientific application. You start from your research problem and compare the options against each other.

We check the source registries daily, so you can see what is new and what is still maintained ↓

“Science is really the engine of progress for civilization but that engine is kind of stalled a little bit. What we really need is open and permissionless science.”

Science should be open to anyone who wants to help move it forward.

That’s the idea behind Bio: open research networks where scientists steer AI agents, share evidence others can build on, and work with communities to fund and develop the science they care about.

The next Ignition Sale is live on Bio!

@NootropicsDAO_ is building NeuroLab AI to predict how compounds could affect the brain, connecting molecular interactions to potential effects on cognition.

The goal: help researchers choose which compounds to test next.

Secure your NDT allocation on Bio: app.bio.xyz/agents/neurola…

Bio Open Lab: NeuroLab AI Ignition Sale x.com/i/spaces/1YxNr…

Starting in 2 HOURS! 🧠

Join us for a discussion with the @NootropicsDAO_ team to explore NeuroLab AI and how it could help researchers understand a compound’s potential effects on the brain.

Diving into their research, what’s being built and what comes next.

Set a reminder below ↓

The first Ignition Sale is expected to go live TOMORROW!

Project: NeuroLab AI by @NootropicsDAO_
Time: Wed Sep 16 @ 2pm UTC

Here’s everything you need to know 🧵↓